Midi Virtuoso Guitar Edition provides a new method of software-based midi play that is focused on simplifying the creation of complex musical parts. The musician, using patent pending Every Key and Trill Pane technologies, “becomes the timeline”. The musician is in complete control of the musical rendering of the notes in a midi part, after sequencing. Timing, duration, and modulation of pre-sequenced notes are controlled in real time. A midi keyboard, computer keyboard and / or mouse can be used to control midi rendering of a sequence and to impart the nuances of real time performance. Designed with the recording musician in mind, Midi Virtuoso can be live-played into digital audio workstation projects, using a virtual midi cable, and rendered via virtual instruments. Midi Virtuoso is useful in live performance situations when a laptop is placed in the midi path, either as the main controller or as a translator between keyboard / controller and sound module. With its keyboard marking features, Midi Virtuoso Guitar Edition also provides teaching / learning features for guitar.